Pediatric Neurology and Endocrinology

The advantage of thyroid hormone treatment for subclinical hypothyroidism is dubious. New evidence from ongoing randomized clinical preliminaries warrants an update of previous meta-analyses. Maybe the most vexing issue in a patient in an intensive care unit (ICU) is a surprising change in mental status. Historically, “acute encephalopathy” was the term used to incorporate such changes; however "delirium" is currently used to portray this state. Newborn screening and gene therapy are energizing new advances in the field of metabolic neurodegenerative disorders. This Viewpoint examines X-connected Adreno Leuko Dystrophy (ALD), an inherited disorder affecting the adrenals and nervous system white matter.

 

  • Juvenile Neurodegeneration
  • Acquired Partial Lipodystrophy
  • Congenital Adrenal Hyperplasia
  • Tay-Sachs Disease
  • Ischaemic Haemorrhagic Stroke

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